UK postgraduate anaesthetic core-science examination
Current Primary FRCA MCQ page, Stage 1 syllabus and curriculum, April 2026 Examination Regulations and 2027 transition guidance reviewed 29 July 2026
601 practice questions
90 flashcards
Completely free

Primary FRCA Written (MCQ) Study Guide

Prepare for 90 five-option Single Best Answer questions by connecting pharmacology, physiology, anatomy, physics, measurement and statistics to practical anaesthesia.

90 SBA
3 hours
3 broad areas

Most popular

Start with free practice questions

Jump into a mixed set drawn from 601 free practice questions.

Free Practice Questions

Exam structure

Know the split before you start drilling

Pharmacology

33.33 items

30 scored + 0 pretest

Physiology, Biochemistry and Anatomy

33.33 items

30 scored + 0 pretest

Physics, Clinical Measurement and Data

33.34 items

30 scored + 0 pretest

Current component

Primary MCQ

This is the written gateway component of the Primary FRCA, not the complete Primary FRCA examination.

Questions

90 SBA

The current paper contains only Single Best Answer questions; MTF items were removed from September 2023.

Time allowed

3 hours

That averages two minutes per question before review time.

Options

5 per question

Each item has a stem or vignette, a lead-in and five plausible options.

Current delivery

Remote online

The RCoA currently delivers the paper online with remote invigilation through TestReach.

Marking

+1 / no penalty

Each correct answer earns one mark; incorrect answers are not negatively marked.

Standard setting

Modified Angoff

The pass mark is set for the paper and is not a fixed percentage published in advance.

Published scope split

About 30 · 30 · 30

The RCoA describes the three areas as broad, non-exclusive proportions rather than guaranteed quotas.

Attempt limit

Maximum 6

The current Regulations add support and evidence requirements before the sixth attempt.

Pass validity

3 years

A current Primary MCQ pass is valid for progression to the Primary OSCE and SOE for three years.

Start here

How to prepare for the current Primary FRCA MCQ

Fix the current format, protect all three science areas and practise explaining every answer from first principles.

1

1. Anchor the current paper

Prepare for one three-hour paper of 90 five-option SBA questions unless the RCoA confirms that your sitting uses the new AKT format.

2

2. Protect the near-equal split

Give pharmacology, physiology with biochemistry and anatomy, and physics with measurement and statistics comparable revision time.

3

3. Build mechanisms before lists

For each fact, explain the causal chain from physical, molecular or physiological principle to the observed anaesthetic consequence.

4

4. Calculate with units

State the relationship, convert units, estimate the direction and magnitude, calculate, then test whether the answer is plausible.

5

5. Rehearse SBA discrimination

Identify the exact lead-in, eliminate options that fail one key condition and choose the single answer that best fits the complete stem.

6

6. Recheck the transition

Confirm the current RCoA calendar and candidate guidance because the planned AKT begins in the 2027–2028 academic year, subject to approval.

About the exam

Primary FRCA Written Exam structure

An independent study guide aligned to the current RCoA Primary FRCA MCQ, Stage 1 examination syllabus and core-science blueprint.

Issuer and path

Primary FRCA Written (MCQ) Study Guide is administered through Royal College of Anaesthetists. Check official resources before booking, retesting, or relying on a stale requirement.

Pharmacology

33.33 items

30 scored + 0 pretest

A broad planning area of about 30 questions covering general pharmacology and anaesthetic, analgesic, neuromuscular, autonomic and perioperative drugs; the live count is not guaranteed.

Physiology, Biochemistry and Anatomy

33.33 items

30 scored + 0 pretest

A broad planning area of about 30 questions covering applied cellular, cardiovascular, respiratory, renal, neurological, endocrine, haematological and anatomical sciences; the live count is not guaranteed.

Physics, Clinical Measurement and Data

33.34 items

30 scored + 0 pretest

A broad planning area of about 30 questions covering physics, equipment, monitoring, clinical measurement, statistics, study design and data interpretation; the live count is not guaranteed.

Confirm the format for your sitting

Use the current RCoA calendar, Regulations, candidate guidance and direct communications to confirm eligibility, application window, technical checks, identification, adjustments and whether your sitting is the legacy MCQ or the new AKT.

Official Outline Coverage Map

Coverage is mapped to official outline item counts so content depth can be checked without hard-coding a single exam.

Official outline
TopicOfficial outline itemsYour questionsYour flashcardsConfidence
Pharmacology30025
Strong
Physiology, Biochemistry and Anatomy30030
Strong
Physics, Clinical Measurement and Data30035
Strong

How to use this guide

How to prepare for the current Primary FRCA MCQ

Build mechanisms first, practise calculations with units, connect equipment to failure modes and finish every SBA by choosing the single best answer to the exact lead-in.

1. Parse the lead-in

Identify whether the item asks for a mechanism, relationship, calculation, instrument principle, physiological change, adverse effect or best application.

2. State the governing principle

Recall the receptor, equation, anatomical relation, conservation law, physiological control loop or study-design rule before inspecting distractors.

3. Predict direction and magnitude

Decide what should rise, fall, shift or remain unchanged; for calculations, convert units and estimate the answer range.

4. Apply the stem conditions

Account for dose, time, patient physiology, organ function, equipment arrangement, measurement limits and any stated assumptions.

5. Eliminate by one decisive flaw

Reject an option that violates the mechanism, unit, direction, anatomy or question wording even if part of it is true.

6. Commit and move on

Select the option that best answers the exact lead-in; there is no negative marking, so leave time for a final review rather than omitting answers.

Current MCQ scope

Cover all three broad areas at near-equal depth

The RCoA says the paper will broadly, but not exclusively, contain about 30 questions from each area.

Pharmacology

A broad planning area of about 30 questions covering general pharmacology and anaesthetic, analgesic, neuromuscular, autonomic and perioperative drugs; the live count is not guaranteed.

30 items

Choose a topic to open below

Physiology, Biochemistry and Anatomy

A broad planning area of about 30 questions covering applied cellular, cardiovascular, respiratory, renal, neurological, endocrine, haematological and anatomical sciences; the live count is not guaranteed.

30 items

Choose a topic to open below

Physics, Clinical Measurement and Data

A broad planning area of about 30 questions covering physics, equipment, monitoring, clinical measurement, statistics, study design and data interpretation; the live count is not guaranteed.

30 items

Choose a topic to open below

Pharmacology
Pharmacology

Pharmacokinetics and Pharmacodynamics

Drug absorption, distribution, protein binding, clearance, compartments, elimination, receptors, dose-response and interactions.

Key rules

Rule 1

Absorption, distribution, protein binding, metabolism and clearance determine the concentration reaching the effect site over time.

Exam cue: Ask whether a change affects loading dose, maintenance dose, effect-site equilibration or more than one of these.

Rule 2

Receptor affinity, efficacy, potency, dose–response shape and patient variability determine the resulting clinical effect.

Exam cue: Separate potency from efficacy and redistribution from elimination.

Common traps

Using elimination half-life alone to predict recovery after a prolonged infusion.

Prevention: Do not choose an option merely because it states a true fact; choose the one that best answers the exact lead-in under the stated conditions.

Assuming that a more potent drug can necessarily produce a greater maximum effect.

Prevention: Do not choose an option merely because it states a true fact; choose the one that best answers the exact lead-in under the stated conditions.

Memory anchors

What mainly determines a loading dose?

Target concentration and apparent volume of distribution, adjusted for bioavailability where relevant.

What mainly determines a maintenance dose rate?

Target concentration and clearance.

What is context-sensitive half-time?

The time for plasma concentration to halve after an infusion stops, considered in relation to infusion duration.

What distinguishes potency from efficacy?

Potency is the concentration or dose needed for an effect; efficacy is the maximum effect achievable.

What does a competitive antagonist usually do?

It shifts the agonist concentration–response curve right without reducing the achievable maximum when sufficient agonist can be given.

Next best moves

Quick check-up

Use a short quiz to confirm the rule pattern is actually sticking.

Check-up Questions

1-2 question checkpoint

After an intravenous bolus, a drug amount falls from 100 mg to 50 mg in 2 hours by first-order elimination. What is its elimination half-life?

Which pharmacokinetic variable relates the amount of drug in the body to its measured plasma concentration?

Answer all questions to submit.

Next step personalized recommendations

Open another topic next

Official resources

Verify the details with the official sources

Use these links for eligibility, scheduling, handbook rules, and issuer updates. Our guide helps you study; official sources tell you what the testing partner currently requires.

FAQ

Common Primary FRCA Written questions

Is this an official RCoA resource?

No. This is an independent study guide. The current Royal College of Anaesthetists examination page, syllabus, regulations, calendar and candidate communications remain authoritative.

What does the primary-frca-written slug cover?

It covers the current written Primary FRCA Multiple Choice Question component. It does not cover the separate Primary FRCA OSCE or SOE and does not represent the complete Fellowship qualification.

What is the current Primary FRCA written format?

The current examination is one remotely invigilated three-hour paper of 90 Single Best Answer questions. Each question has a stem or vignette, a lead-in and five plausible options, from which the candidate chooses the best answer.

Does the current paper contain Multiple True/False questions?

No. The RCoA removed Multiple True/False questions from September 2023. The current paper is 90 SBA questions, and the College states that the change did not alter the MCQ blueprint.

What are the three published MCQ areas?

The paper will broadly, but not exclusively, contain about 30 questions in pharmacology; 30 in physiology including related biochemistry and anatomy; and 30 in physics, clinical measurement, statistical methods and data interpretation.

Are the three 30-question allocations fixed?

No. The RCoA deliberately says broadly, but not exclusively. This guide uses the three areas as near-equal planning weights and does not claim that every live paper contains exactly 30 questions from each.

How does the Stage 1 curriculum relate to this paper?

The MCQ is aligned to the Stage 1 UK anaesthetics curriculum and tests the breadth and level of core science needed for practical anaesthesia and anaesthesia-related medicine. The whole Primary FRCA assessment samples the syllabus, while the written paper focuses on curriculum codes designated for the MCQ.

Does passing the MCQ complete the Primary FRCA?

No. The current MCQ is a gateway: candidates must pass it before applying for the Primary FRCA OSCE and SOE. The complete Primary FRCA requires the applicable components under the current Regulations.

How is the MCQ marked?

A correct answer earns one mark, for a maximum of 90, and there is no negative marking. Examiners provisionally set the pass mark using a modified Angoff method and may remove an erroneous or ambiguous item without disadvantaging candidates.

Who is eligible to sit the MCQ?

Eligibility depends on medical registration and an eligible RCoA trainee or recognised membership route, together with the attempt rules. The current examination page gives a summary; candidates should use Section 4 of the current Regulations for the complete rule.

How many attempts are allowed?

The current Regulations allow a maximum of six attempts at an examination component. A candidate proceeding to a sixth attempt must meet the Additional Educational Training and guidance requirements described in the Regulations.

Is the written examination changing in 2027?

Yes. The RCoA plans to introduce the Primary FRCA Applied Knowledge Test from July 2027, subject to GMC approval. The published new format is two papers of 80 SBA questions, each lasting two hours 20 minutes. The 2026–2027 academic year remains the final year of the current format, so candidates must follow the timetable and format for their own sitting.

Does the planned AKT change the syllabus?

The RCoA transition FAQ says the curriculum has not changed and questions will continue to be drawn from the current published curriculum and syllabus. The delivery structure changes, but this module records the current MCQ as authoritative until the new format takes effect.

Are the 601 practice questions an official number?

No. Ninety is the current live-exam question count. The 601 original practice items are a study-bank allocation: 201 cover pharmacology and 200 cover each of the other two broad areas.

What is Pass Harbor?

Completely free exam prep for 247 UK exams.

  • Practice questions
  • Flashcards
  • Study guides
  • Mock exams
  • No registration
  • No paywall
  • Start instantly
No more expensive exam prep. Quality study tools should be accessible to everyone.