UK Prescribing Safety Assessment study guide
Prescribing Safety Assessment Blueprint dated 14 July 2025 and current official candidate guidance reviewed 29 July 2026
601 practice questions
120 flashcards
Completely free

Prescribing Safety Assessment Study Guide

Build a repeatable safe-prescribing process across all eight PSA item styles, seven clinical settings and five guaranteed high-risk medicine groups.

60 items · 120 minutes
8 item styles
BNF · BNFc access

Most popular

Start with free practice questions

Jump into a mixed set drawn from 601 free practice questions.

Free Practice Questions

Exam structure

Know the split before you start drilling

Prescribing

40%

8 scored + 0 pretest

Prescription Review

16%

8 scored + 0 pretest

Planning Management

8%

8 scored + 0 pretest

Providing Information

6%

6 scored + 0 pretest

Calculation Skills

8%

8 scored + 0 pretest

Adverse Drug Reactions

8%

8 scored + 0 pretest

Drug Monitoring

8%

8 scored + 0 pretest

Data Interpretation

6%

6 scored + 0 pretest

Assessment length

60 items

The current blueprint contains 60 items across eight item styles.

Time allowed

120 minutes

Candidates are expected to complete the online assessment in two hours.

Total marks

200

Prescribing contributes 80 marks and Prescription Review contributes 32; the other six sections contribute 12 or 16 marks each.

Item styles

8

Prescribing, Prescription Review, Planning Management, Providing Information, Calculation Skills, Adverse Drug Reactions, Drug Monitoring and Data Interpretation.

Clinical settings

7

Medicine, Surgery, Elderly Care, Paediatrics, Psychiatry, Obstetrics & Gynaecology and General Practice.

High-risk coverage

5 groups

The official sampling matrix requires coverage of opioids, anticoagulants, insulins, antibiotics and infusion fluids; it does not publish a fixed minimum for each group.

Permitted references

BNF · BNFc

Online BNF and BNF for Children resources are available through the PSA interface, within the official access restrictions.

Pass standard

Paper-specific

The exact pass mark is set using the Modified Angoff method and is not fixed in advance.

Start here

How to prepare for the PSA

Learn the safety process first, then add item-style technique and timed source use.

1

1. Learn the eight response formats

Know which sections require a structured prescription, two linked chart-review selections, one of five options or a numeric answer.

2

2. Build one safe-prescribing sequence

For every scenario, confirm the indication and patient, review existing treatment and risks, select and calculate carefully, then communicate and monitor.

3

3. Practise BNF and BNFc navigation

Use the permitted resources to verify dose, contraindication, interaction and administration details without losing track of the clinical question.

4

4. Rotate settings and high-risk medicines

Revisit each item style across all seven clinical settings, giving extra independent checks to the five guaranteed high-risk groups.

5

5. Use the official practice interface

Complete the official practice papers supplied through your school to rehearse prescription entry, numeric responses, BNF access and two-hour pacing.

About the exam

PSA Exam structure

An independent study guide aligned to the current Prescribing Safety Assessment blueprint for safe and effective medicines use at Foundation Year 1 level.

Issuer and path

Prescribing Safety Assessment Study Guide is administered through MSC Assessment and the British Pharmacological Society. Check official resources before booking, retesting, or relying on a stale requirement.

Prescribing

40%

8 scored + 0 pretest

Eight prescription-writing items worth 10 marks each: five marks for drug choice and five for dose, route and frequency.

Prescription Review

16%

8 scored + 0 pretest

Eight chart-review items, each with two linked tasks and worth four marks, focused on unsafe, ineffective or inappropriate prescriptions.

Planning Management

8%

8 scored + 0 pretest

Eight items selecting the most appropriate initial management option for the individual clinical situation.

Providing Information

6%

6 scored + 0 pretest

Six items selecting the most important medicine information for a patient, carer or healthcare professional.

Calculation Skills

8%

8 scored + 0 pretest

Eight numeric-response items covering safe dose, quantity, concentration, dilution, volume, duration or administration-rate calculations.

Adverse Drug Reactions

8%

8 scored + 0 pretest

Eight items covering adverse effects, causative medicines, clinically important interactions and management of adverse events.

Drug Monitoring

8%

8 scored + 0 pretest

Eight items selecting the best objective measure and timing for beneficial or harmful effects of treatment.

Data Interpretation

6%

6 scored + 0 pretest

Six items interpreting investigation results and choosing the appropriate change to ongoing prescribing.

Before your sitting

Your medical or foundation school arranges registration and the local sitting. Activate the account when instructed, complete the official practice papers, confirm reasonable adjustments and local calculator rules, and use only the permitted BNF and BNFc routes during the assessment.

Official Outline Coverage Map

Coverage is mapped to official outline item counts so content depth can be checked without hard-coding a single exam.

Official outline
TopicOfficial outline itemsYour questionsYour flashcardsConfidence
Patient and Indication Assessment3815
Priority
Medicine Selection and Reliable Source Use3805
Priority
Complete and Practical Prescriptions2805
Strong
Medication-List Reconciliation3325
Strong
Interactions, Contraindications and Patient-Specific Adjustment3325
Priority
Errors, Optimisation and Deprescribing2325
Priority
Initial Treatment Prioritisation3165
Strong
Acute Emergencies and Toxicology3165
Priority
Individualisation and Non-Drug Options2165
Good
Purpose, Benefits and Shared Decisions2125
Strong
Instructions, Warnings and Safety-Netting2125
Priority
Team Communication and Documentation2125
Good
Units, Concentrations and Conversions3165
Priority
Dose, Quantity and Patient-Size Calculations3165
Priority
Infusions, Dilutions and Fluids2165
Priority
Adverse Effects and Causative Medicines3165
Priority
Clinically Important Interactions3165
Priority
Adverse-Event Management, Prevention and Reporting2165
Strong
Baseline and Safety Monitoring3165
Priority
Efficacy Monitoring and Timing3165
Strong
Monitoring Trends and Escalation2165
Strong
Laboratory Results, Organ Function and Drug Concentrations2125
Priority
Charts, Nomograms and Clinical Observations2125
Good
From Data to Prescribing Action2125
Priority

How to use this guide

How to prepare for the PSA

Combine patient-centred prescribing judgement with fast BNF navigation, reliable calculations, complete prescriptions and explicit monitoring and communication.

1. Define the patient and purpose

Confirm the indication, immediate treatment objective, allergies, medication history and patient factors that alter benefit or risk.

2. Review medicines and hazards

Check current treatment, contraindications, interactions, organ function, pregnancy, duplication and the five guaranteed high-risk medicine groups.

3. Select and verify

Choose the safest effective option for this patient and use the permitted BNF or BNFc resource to verify precise medicine information.

4. Calculate and write clearly

Convert units, check magnitude and produce a complete, practical and unambiguous prescription or numeric response.

5. Communicate, monitor and close the loop

Give the most important information, define benefit and safety monitoring, document the decision and escalate uncertainty or urgent risk.

Official item-style map

Train the response format as well as the clinical decision

The eight official sections assess different actions, so organise practice around what each task asks you to produce.

Safe Prescription Writing

Patient assessment, medicine selection and complete, practical prescriptions for one drug or intravenous fluid.

241 items

Choose a topic to open below

Safe Prescription Review

Systematic review of medication lists for errors, interactions, contraindications, inefficacy and opportunities to optimise treatment.

96 items

Choose a topic to open below

Individualised Management Planning

Selecting an initial treatment, including when to withhold treatment, use a non-drug option or escalate an emergency.

48 items

Choose a topic to open below

Medicines Communication

Prioritising information that supports informed choice and safe, effective medicine use by patients and clinical teams.

36 items

Choose a topic to open below

Safe Prescribing Calculations

Unit-aware dose, quantity, concentration, dilution, infusion and fluid calculations with a reasonableness check.

48 items

Choose a topic to open below

Adverse Effects and Interactions

Recognising, preventing and managing adverse reactions and clinically important medicine interactions.

48 items

Choose a topic to open below

Therapeutic Monitoring

Planning baseline, efficacy and safety monitoring with the correct measure, timing and escalation route.

48 items

Choose a topic to open below

Prescribing Data Interpretation

Turning laboratory, physiological and medicine-concentration data into a safe prescribing action.

36 items

Choose a topic to open below

Safe Prescription Writing
Prescribing

Patient and Indication Assessment

Establish the prescribing purpose and identify patient factors that change the benefit, risk, formulation, route or dose.

Key rules

Rule 1

A safe prescription begins with a clear indication and an accurate account of current and recent medicines, allergies and previous adverse reactions.

Exam cue: State the indication and the intended benefit before choosing a medicine.

Rule 2

Age, body size, pregnancy, frailty, kidney or liver impairment, comorbidity and the practical route of administration can materially change a prescription.

Exam cue: Check allergies, existing medicines, organ function and patient-specific contraindications.

Rule 3

The clinical scenario must be interpreted before consulting a medicines reference; a formulary does not decide whether treatment is appropriate for this patient.

Exam cue: Separate information that changes the prescription from background detail.

Common traps

Searching for a dose before confirming the indication and patient.

Prevention: Do not let a familiar medicine, reference search or calculator output replace patient-specific safety checks and escalation.

Ignoring non-prescription medicines, recent treatment or a documented adverse reaction.

Prevention: Do not let a familiar medicine, reference search or calculator output replace patient-specific safety checks and escalation.

Treating a standard adult dose as automatically suitable for every patient.

Prevention: Do not let a familiar medicine, reference search or calculator output replace patient-specific safety checks and escalation.

Memory anchors

Indication First

Define the problem and intended treatment benefit before selecting a medicine.

Medication History

Include prescribed, over-the-counter, complementary and recently stopped medicines.

Allergy Check

Distinguish a documented allergy from an intolerance while treating both as relevant history.

Patient Factors

Age, size, pregnancy, frailty and organ function can change medicine choice or dose.

Clinical Context

Use the BNF within the patient scenario rather than as a substitute for clinical judgement.

Next best moves

Quick check-up

Use a short quiz to confirm the rule pattern is actually sticking.

Check-up Questions

1-2 question checkpoint

A 72-year-old with vomiting has BP 86/54 mmHg, cool peripheries and no pulmonary oedema. What treatment need should be addressed first?

A patient with type 1 diabetes is vomiting, glucose 24 mmol/L, ketones 6 mmol/L and venous pH 7.18. Which need is most urgent?

Answer all questions to submit.

Next step personalized recommendations

Open another topic next

Official resources

Verify the details with the official sources

Use these links for eligibility, scheduling, handbook rules, and issuer updates. Our guide helps you study; official sources tell you what the testing partner currently requires.

FAQ

Common PSA questions

Is this an official MSC Assessment or BPS resource?

No. This is an independent study guide. The current PSA Blueprint, official candidate information and the materials made available through your medical or foundation school remain authoritative.

What are the eight PSA item styles?

The assessment contains Prescribing, Prescription Review, Planning Management, Providing Information, Calculation Skills, Adverse Drug Reactions, Drug Monitoring and Data Interpretation. Each style has its own response format and mark allocation.

What clinical domains does the current PSA cover?

The official blueprint calls them clinical settings: Medicine and Elderly Care each have a minimum of eight items; General Practice also has eight; Surgery, Paediatrics, Psychiatry and Obstetrics & Gynaecology each have a minimum of four. These minima account for 40 items, with the complete paper sampling matrix assigning the remaining items while preserving blueprint coverage.

What does the PSA assess?

It assesses safe and effective prescribing at the level expected of a Foundation Year 1 doctor: choosing and writing prescriptions, reviewing existing prescriptions, planning treatment, communicating medicine information, calculating doses, recognising and managing adverse reactions, monitoring therapy and acting on clinical data. It is not primarily a diagnostic examination.

How are prescribing items marked?

There are eight prescribing items worth ten marks each. Five marks relate to drug choice and five to the dosage components of dose, route and frequency. The task requests one medicine or, when explicitly stated, one intravenous fluid.

Are all PSA items multiple-choice questions?

No. Prescribing items use a structured prescription response and Calculation Skills items require a numeric answer. Prescription Review has two linked selection tasks, while the other item styles generally ask for the best option from five. Use the official practice papers to rehearse the actual interface.

Can I use the BNF during the PSA?

Yes. The official interface provides access to online BNF and BNFc resources through Medicines Complete and NICE. The permitted scope does not include unrelated NICE guidance, Clinical Knowledge Summaries or external links, and the BNF cannot replace interpretation of the patient scenario.

Is there a fixed PSA pass mark?

No fixed score can be published before a sitting. The official Standard Setting Group uses the Modified Angoff method and the final mark may account for paper difficulty and post-assessment item review.

Why does this guide not claim to provide a full simulated PSA?

The current Pass Harbor question framework does not reproduce the official structured prescription-writing fields or unrestricted numeric-response format. This guide supports the underlying skills, but the official 60-item practice paper is the appropriate source for authentic interface familiarisation.

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