Haematology, Coagulation and Transfusion
Classify anaemia, recognise haematological emergencies, manage bleeding or thrombosis and prescribe blood products safely.
How to prepare for PLAB 1
Practise recognising the immediate clinical task, ruling in or out dangerous alternatives, choosing the safest next step and closing the loop.
Core concepts
Concept 1
A full blood count is interpreted through cell lines, indices, smear, clinical context and trend.
Exam cue: Identify immediate bleeding, infection, thrombosis or cell-count danger.
Concept 2
Blood products are prescribed treatments requiring identity checks, indication, consent, monitoring and reaction management.
Exam cue: Use mechanism to direct testing rather than ordering an undifferentiated panel.
Risk pitfalls and guardrails
Transfusing a number without clinical indication.
Guardrail: Avoid an option that names a plausible diagnosis but ignores physiology, contraindications, competence, patient priorities or follow-up.
Continuing a transfusion when a serious reaction is suspected.
Guardrail: Avoid an option that names a plausible diagnosis but ignores physiology, contraindications, competence, patient priorities or follow-up.
Memory anchors
How is anaemia approached?
Severity, acuity, red-cell size, reticulocyte response, bleeding, haemolysis and production causes.
What makes neutropenic sepsis urgent?
Possible infection with significant neutropenia needs immediate pathway-based antibiotics and escalation.
What frames anticoagulant bleeding?
Severity, drug and timing, renal function, source control and indicated reversal.
What follows a suspected transfusion reaction?
Stop the transfusion, maintain access, assess and treat, check identity, notify and investigate.
What makes transfusion appropriate?
A defined clinical indication with alternatives, patient factors and benefit-harm assessment.
Checkpoint rule
Do the check-up only after you can summarize each concept in one sentence and identify one dangerous pitfall from memory.
Knowledge Check (after reading)
Short check-up to confirm understanding of this module.
Check-up Questions
A 68-year-old man has iron-deficiency anaemia without obvious bleeding. What is best?
A patient has macrocytosis, neuropathy and glossitis. What deficiency is likely?
Answer all questions to submit.
Next step personalized recommendations
Continue learning
Move forward only after this module is stable.
What is Pass Harbor?
Completely free exam prep for 247 UK exams.
- Practice questions
- Flashcards
- Study guides
- Mock exams
- No registration
- No paywall
- Start instantly
“No more expensive exam prep. Quality study tools should be accessible to everyone.”
