Acute Care, Infection and Prescribing
Apply ABCDE, sepsis recognition, antimicrobial stewardship and calculation-safe prescribing across clinical systems.
How to prepare for PLAB 1
Practise recognising the immediate clinical task, ruling in or out dangerous alternatives, choosing the safest next step and closing the loop.
Core concepts
Concept 1
Acute care integrates physiology, early escalation, treatment of reversible causes and closed-loop review.
Exam cue: Treat the immediate threat while collecting only information that changes care.
Concept 2
Safe prescribing requires patient, indication, medicine, dose, route, frequency, interactions, monitoring and documentation.
Exam cue: Perform a final units, dose and plausibility check.
Risk pitfalls and guardrails
Delaying sepsis treatment while seeking diagnostic certainty.
Guardrail: Avoid an option that names a plausible diagnosis but ignores physiology, contraindications, competence, patient priorities or follow-up.
Copying a medicine without reconciling indication and current physiology.
Guardrail: Avoid an option that names a plausible diagnosis but ignores physiology, contraindications, competence, patient priorities or follow-up.
Memory anchors
What is the purpose of ABCDE?
Find and treat immediate threats in priority order, then reassess after each intervention.
What makes infection sepsis?
Life-threatening organ dysfunction caused by a dysregulated response to infection.
What belongs in antimicrobial choice?
Likely source and organism, severity, allergy, renal function, local guidance, cultures and review.
What is medicines reconciliation?
Build the most accurate list, compare it with current orders and resolve discrepancies.
What is the final calculation check?
Units, patient factors, route, frequency, maximum, decimal safety and clinical plausibility.
Checkpoint rule
Do the check-up only after you can summarize each concept in one sentence and identify one dangerous pitfall from memory.
Knowledge Check (after reading)
Short check-up to confirm understanding of this module.
Check-up Questions
An unresponsive inpatient is found with noisy breathing. What is the first action?
A patient is high risk for sepsis with hypotension, confusion and raised lactate. What is best?
Answer all questions to submit.
Next step personalized recommendations
Continue learning
Move forward only after this module is stable.
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